For some reasons, when you open the commands menu while you're in the middle of a run on a map, you're set back to the start of the said map.
It occured yesterday to a friend, here's the Twitch Clip (french; i let a bit of salt at the start as an extra; issue seen at ~19s) :
We were on Maniacisco map (TM RPG), he was already quite angry on this cp12 at the backwards free wheel part where he kept getting... bamboozled

I know that for some reasons (? replays related maybe ?), when you bind some keys they'll not work on the fly. But forcing an auto give up is a bit too much.
I tried to reproduce it myself, i couldn't. On his end however it's reproducible and occur 100% of the time.
*Okay, almost all. There was still "U" binded to give up (cf. start of the VOD). But he tried again a few minutes ago after unbinding it and he still got a restart.
Update : Somehow he bound give up on his left mouse click...